<International Circulation>:You talked about intracranial pressure as well， how well are intracranial pressure and central pressure related? 
  《国际循环》：您同时也讲到了颅内压，请问颅内压和中心血压有什么紧密的关系吗？
    Prof. Alvolio : Intracranial pressure waveform seems to be reasonably similar to the arterial pressure. It is not possible to measure pressure in the skull， so the closest one can get to this is to measure the carotid pressure which is quite close to the central aortic pressure. If one can estimate central aortic pressure， some analysis can be done on that to estimate intracranial pressure. The estimation of the wave form of intracranial pressure has some features associated with the type of tissue and fluid structure. If you have increased intracranial pressure， the brain becomes stiffer which appears to be a way that you can validate and quantify that difference. 
    Alvolio教授：颅内压波形似乎和动脉压很相似。由于不能在颅骨内测量压力，因此最接近颅内压的是测量颈动脉压力，而颈动脉压力和中心动脉压力又非常接近。如果我们能对中心动脉压进行测算，我们也能通过一些分析对颅内压进行估量。对颅内压波形的测量有一些与组织和流体构造类型相关的特征。如果颅内压增高，大脑的硬度就会增加，这样就能确定并定量化那些差异。